Searchable abstracts of presentations at key conferences in endocrinology

ea0002p58 | Growth and development | SFE2001

MOLECULAR EVOLUTION OF GROWTH HORMONE IN CETARTIODACTYLA

Maniou Z , Wallis O , Sami A , Wallis M

The sequence of pituitary growth hormone (GH) is generally strongly conserved in mammals, but short bursts of rapid change during the evolution of primates and artiodactyls have led to marked differences in primary structure and biological specificity in human and ruminant GHs. Recent molecular studies have shown that Cetacea are nested within Artiodactyla, and the combined grouping (Artiodactyla and Cetacea) has been termed the Cetartiodactyla. To explore further GH evolution...